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Because the review permits randomized comparisons of a GLP1ra and an SGLT2i in subgroups and includes OGTT info, we contrasted the consequences from the review compounds on fasting and postprandial steps. Though semaglutide resulted in overall bigger glycaemic improvements, it is notable that the effect of dapagliflozin relative to semaglutide was much larger on fasting than postprandial results. The outcome of dapagliflozin on fasting glucose was fifty seven% relative to that of semaglutide, Whilst the effect of dapagliflozin on 2-h glucose was only 38% compared with that of semaglutide (Desk two and Supplementary Table four).
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